From the 73, merge onto the 55 freeway South, 55 South ends and becomes Newport Boulevard. From Newport Boulevard merge onto Pacific Coast Highway (1) Northbound. Turn Right onto Hoag Drive. Look for the Hoag Cancer Center Building on the left.

From the 5, take the 55 south, 55 South ends and becomes Newport Boulevard. From Newport Boulevard merge onto Pacific Coast Highway (1) Northbound. Turn Right onto Hoag Drive. Look for the Hoag Cancer Center Building on the left.

From the 405, take the 405 to the 55 South, 55 South ends and becomes Newport Boulevard. From Newport Boulevard merge onto Pacific Coast Highway (1) Northbound. Turn Right onto Hoag Drive. Look for the Hoag Cancer Center Building on the left.